• Hypothalamic clock involvement in cluster headache. A study of chronobiology, sleep, and cranial autonomic function in cluster headache 

      Ofte, Hilde Karen (Doctoral thesis; Doktorgradsavhandling, 2016-10-24)
      Cluster headache has been claimed to be a chronobiological disorder because of its striking periodic occurrence. This suggests that the biological clock is involved in the pathophysiology of the disease, but few researchers have studied this in depth. In this thesis, we have studied several aspects of chronobiology in cluster headache patients. First, we assessed the periodicity of headache attacks, ...
    • Kjernevåpen og helseeffekter 

      Ofte, Hilde Karen; Jakobsen, Kristin Alise (Master thesis; Mastergradsoppgave, 2004)
    • Lack of association between cluster headache and PER3 clock gene polymorphism 

      Ofte, Hilde Karen; Tronvik, Erling Andreas; Alstadhaug, Karl Bjørnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-02-29)
      Background Cluster headache (CH) is regarded as a chronobiological disorder. The hypothalamic biological clock may thus be involved in the pathophysiology, but few studies have actually investigated this in CH patients. A variable number tandem repeat (VNTR) polymorphism of the PER3 clock gene has been associated to preferred daily rhythm (chronotype) in several studies. We aimed to study the ...
    • Patient satisfaction with conventional, complementary, and alternative treatment for cluster headache in a Norwegian cohort 

      Bekkelund, Svein Ivar; Ofte, Hilde Karen; Alstadhaug, Karl Bjørnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • Praktisk håndtering av hodepine 

      Aamodt, Anne Hege; Bjørk, Marte-Helene; Alstadhaug, Karl Bjørnar; Eldøen, Guttorm; Dueland, Aud Nome; Poole, Tine; Hagen, Knut; Vetvik, Kjersti; Ofte, Hilde Karen; Sønnervik, Julie; Kristoffersen, Espen Saxhaug; Winsvold, Bendik K S; Lundqvist, Christofer; Sagabråten, Ståle Onsgår (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-03)
      Korrekt diagnostikk av ulike hodepinetyper kan være utfordrende, men det er den viktigste forutsetningen for optimal behandling. Det anbefales kontrollert bruk av anfallsmedisin og forebyggende tiltak.<p> <p>Hodepinesykdommer er ifølge sykdomsbyrdeprosjektet Global Burden of Disease blant de vanligste årsakene til funksjonsnedsettelse (1). Lidelsene påvirker i stor grad samfunnet, personene som ...
    • Preventing and treating medication overuse headache 

      Alstadhaug, Karl Bjørnar; Ofte, Hilde Karen; Kristoffersen, Espen Saxhaug (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-01)
      The concept that headache treatment per se may be the cause of chronification of headache is not new,3 but our understanding of this concept, and the terminology defining it, have changed throughout the years. The criteria for MOH are based on expert consensus rather than formal evidence. According to the current definition in the latest (2013) International Classification of Headache Disorders–3 ...
    • Sudden caffeine withdrawal triggers migraine—A randomized controlled trial 

      Alstadhaug, Karl Bjørnar; Ofte, Hilde Karen; Müller, Kai Ivar; Andreou, Anna P. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-10)
      <i>Objective</i>: Assessing the effects of caffeine withdrawal on migraine.<p> <p><i>Background</i>: The effects of caffeine withdrawal on migraineurs are at large unknown.<p> <p><i>Methods</i>: This was a randomized, double-blind, crossover study (NCT03022838), designed to enroll 80 adults with episodic migraine and a daily consumption of 300–800 mg caffeine. Participants substituted their ...